GLOSSARY ENTRY (DERIVED FROM QUESTION BELOW) | ||||||
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14:51 Aug 13, 2015 |
Polish to English translations [PRO] Science - Genetics / general | |||||
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| Selected response from: Frank Szmulowicz, Ph. D. United States Local time: 11:20 | ||||
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Summary of answers provided | ||||
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3 +3 | loss of a gene |
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2 | lacking the gene |
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Discussion entries: 3 | |
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lacking the gene Explanation: . -------------------------------------------------- Note added at 17 mins (2015-08-13 15:09:19 GMT) -------------------------------------------------- Handbook of Multiple Sclerosis, Third Edition https://books.google.co.uk/books?isbn=0824741846 Stuart D. Cook - 2001 - Medical Histological examination of the spinal cord demonstrated a lack of ... disease when compared with mice infected with a control construct lacking the PLP gene. |
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loss of a gene Explanation: Yes, gene knockout is another term. -------------------------------------------------- Note added at 20 mins (2015-08-13 15:11:41 GMT) -------------------------------------------------- Option 2removal of a gene -------------------------------------------------- Note added at 9 hrs (2015-08-13 23:56:22 GMT) -------------------------------------------------- CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC option 3: inactivation of a gene CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC cccccccccccccccccccccccccccc Gene knockout: loss of a gene can be compensated by another gene http://www.mpg.de/9331068/knockout-knockdown ccccccccccccccccccccc A knockout mouse or knock-out mouse is a genetically modified mouse in which researchers have inactivated, or "knocked out", an existing gene by replacing it or disrupting it with an artificial piece of DNA. The loss of gene activity often causes changes in a mouse's phenotype, which includes appearance, behavior and other observable physical and biochemical characteristics. The loss of gene activity often causes changes in a mouse's phenotype, which includes appearance, behavior and other observable physical and biochemical https://en.wikipedia.org/wiki/Knockout_mouse ccccccccccccccccccc What is a knockout mouse? A knockout mouse is a laboratory mouse in which researchers have inactivated, or "knocked out," an existing gene by replacing it or disrupting it with an artificial piece of DNA. The loss of gene activity often causes changes in a mouse's phenotype, which includes appearance, behavior and other observable physical and biochemical characteristics. https://www.genome.gov/12514551 |
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