English to Arabic Bus/Financial Medical: Cardiology Medical Legal

Arabic meaning of (iPSC­‐derived cardiomyocytes)



Context:

Our hypothesis will be tested by pursuing the following specific aims:
1) To create a UAE genotype-­‐specific iPSC library by epigenetically reprogramming control and patient-­‐specific
peripheral blood mononuclear cells or urinary epithelial cells,

2) To perform in depth characterization of the developed iPSC library including karyotypic analysis,
cell-­‐surface antigen expression analysis, gene expression analysis, and establish their differentiation potential,

3) To establish in vitro cultures of iPSC-­‐derived cardiomyocytes from control and diseased individuals
for the study of electrophysiological functional parameters and examine the pharmacological or toxicological
effect at a functional level of currently utilized drugs. Ultimately we aim to share the iPSC Biobank with the local
and international scientific community.