carry-over progressive multifocal leukoencephalopathy

Russian translation: см.

09:47 Dec 18, 2021

English to Russian translations [PRO]
Medical - Medical: Pharmaceuticals

English term or phrase: carry-over progressive multifocal leukoencephalopathy

One confirmed confounded carry-over case resulted in fatal outcome (69 years old female died due to carry-over progressive multifocal leukoencephalopathy associated with natalizumab). Of the 10 confirmed confounded cases, one case in a 78 year old male is non- carry-over case from prior DMTs which resulted in fatality on an unknown date with cause of death not reported. In this case, the potential contribution of ocrelizumab treatment for developing PML is difficult to quantify but cannot be ruled out.

Anastasia Serdyukova KudoZ activity Questions: 4811 (none open) (20 closed without grading) Answers: 0 Russian Federation
Local time: 21:21

Russian translation:см.

Explanation:
Один подтвержденный случай искажения [эффекта терапии] с летальным исходом был обусловлен ***следовым эффектом предшествующей терапии*** (женщина 69 лет умерла вследствие ***прогрессирующей мультифокальной лейкоэнцефалопатии, которая являлась следовым эффектом предшествующей терапии*** натализумабом). Один из 10 подтвержденных случаев искажения [эффекта] с летальным исходом у 78-летнего мужчины не был обусловлен ***следовым эффектом*** предшествующей терапии DMT [терапии, модифицирующей течение РС]...

Confounding is an important source of bias in nonexperimental studies, arising when the effect of an exposure on the occurrence of an outcome is distorted by the effect of some other factor.
https://pubmed.ncbi.nlm.nih.gov/22364797/

https://www.proz.com/kudoz/english-to-russian/medical-genera...

Selected response from:

Margarita Vidkovskaia
Russian Federation
Local time: 21:21

Grading comment

4 KudoZ points were awarded for this answer

Summary of answers provided

4 +1

Прогрессирующая мультифокальная лейкоэнцефалопатия вследствие эффекта переноса

Tymur Buliekov

см.

Margarita Vidkovskaia

Answers

57 mins confidence:

peer agreement (net): +1

Прогрессирующая мультифокальная лейкоэнцефалопатия вследствие эффекта переноса

Explanation:
Вот здесь еще обсуждалось — https://www.proz.com/kudoz/english-to-russian/medical-cardio...

Example sentence(s):

Такой дизайн имеет недостатки всех перекрестных исследований: если в исследуемых группах много выбываний, могут возникнуть аналитические
При лечении ревматоидного артрита (РА) ритуксимабом (РТМ) возможны различные неблагоприятные реакции, среди которых особое место занимает

https://rsp.mediar-press.net/rsp/article/view/2600?locale=ru_RU
https://www.consultant.ru/document/cons_doc_LAW_320321/dbaca3bdc8a38c35c0b933fc36793422c4fd7d4b/

Tymur Buliekov
Ukraine
Local time: 21:21
Specializes in field
Native speaker of:

Russian,

Ukrainian
PRO pts in category: 80

9 hrs confidence:

см.

Margarita Vidkovskaia
Russian Federation
Local time: 21:21
Specializes in field
Native speaker of:

Russian
PRO pts in category: 964

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