English to Romanian Medical Medical (general) Medical

Buna ziua,

As avea nevoie de ajutor pentru traducerea structurii "down-regulated" in limba romana.

Context:
"Nevertheless, most studies of plasmapheresis or plasma exchange combined with immunosuppressive agents for treatment of various autoimmune diseases have reported that cellular immunity was down-regulated in terms of decreased numbers of total T cells and B cells and increases in suppressor T cells."

Va multumesc anticipat pentru orice ajutor acordat!