Glossary entry (derived from question below)
Chinese term or phrase:
壬二酸二氨基酸乙酯
English translation:
N,N’-azelaoyl diaminoacid ethyl ester
Added to glossary by
DKDL
Feb 14, 2016 14:23
8 yrs ago
Chinese term
壬二酸二氨基酸乙酯
Chinese to English
Science
Chemistry; Chem Sci/Eng
Chemical compound
壬二酸二氨基酸乙酯是整个合成反应中的中间产 物,实验采用改进的肖顿-鲍曼缩合反应,利用非质子溶剂和无水盐建立无水状态合成壬二酸二氨基酸乙酯。
I am having trouble with the ordering of the words in translating this chemical compound. The ordering of individual words in English may be different from that of the Chinese source. But I've found several and could not determine the correct one, or the one used most prevalently in scholarly writing of this chemical compound in English. Would much appreciate any help here.
I am having trouble with the ordering of the words in translating this chemical compound. The ordering of individual words in English may be different from that of the Chinese source. But I've found several and could not determine the correct one, or the one used most prevalently in scholarly writing of this chemical compound in English. Would much appreciate any help here.
Proposed translations
(English)
| 5 | N,N’-azelaoyl diaminoacid ethyl ester |
ysun
|
| 4 | Azelaic acid (diethyl ester) |
Erzsébet Czopyk
|
Proposed translations
4 hrs
Selected
N,N’-azelaoyl diaminoacid ethyl ester
壬二酸二氨基酸乙酯 actually means 壬二酰基二氨基酸乙酯. I would use N,N’-azelaoyl diaminoacid ethyl ester for 壬二酸二氨基酸乙酯. You may not be able to find this English name in academic papers because it refers to a family of similar chemicals, but this name is in accordance with nomenclature rules. Meanwhile, N,N’-azelaic acid diaminoacid ethyl ester may also be acceptable.
Please take a look at this picture:
http://patentimages.storage.googleapis.com/CN102388017B/CN10...
This picture is from paragraph [0044] of this patent (一种壬二酸的氨基酸衍生物的合成方法 ):
http://www.google.com/patents/CN102388017B?cl=zh
The formula in this picture depicts N,N’-azelaoyl diaminoacetic acid ethyl ester (壬二酰基二氨基乙酸乙酯). “N,N’-” is used to make it clear that the azelaoyl group is connected with the two amono group (-NH2-) at both ends.
Please take a look at this picture:
http://patentimages.storage.googleapis.com/CN102388017B/CN10...
This picture is from paragraph [0044] of this patent (一种壬二酸的氨基酸衍生物的合成方法 ):
http://www.google.com/patents/CN102388017B?cl=zh
The formula in this picture depicts N,N’-azelaoyl diaminoacetic acid ethyl ester (壬二酰基二氨基乙酸乙酯). “N,N’-” is used to make it clear that the azelaoyl group is connected with the two amono group (-NH2-) at both ends.
4 KudoZ points awarded for this answer.
Comment: "Thank you for the great answer!"
40 mins
Erzsébet Czopyk
Hungary
Hungary
Hungary
sworn translator, linguist, DPO
Native in: Hungarian (Variant: Hungary) 
Works in: Russian to Hungarian, Hungarian to Russian, Latvian to Russian, and 10 more.
Related KudoZ points
:
4
Azelaic acid (diethyl ester)
Roughly: Azelaic acid diethyl ester is an intermediate product via synthesis reaction, experiments using an improved Schotten - Baumann condensation reaction
Catalytic Approaches to the Synthesis of Amide Bonds - Opus
opus.bath.ac.uk/29484/1/UnivBath_PhD_2012_C.L.Allen.pdf
by C Allen -
Results and Discussion IV - Amides from Carboxylic Acids. 112. 5.1 Introduction. 113 .... spray is synthesised using the Schotten-Baumann reaction.
Patent US5051466 - Internal mold release compositions ...
www.google.com/patents/US5051466
Sep 24, 1991 - It is released from the salt by the reaction of the amine with the ... The present invention provides for an improvement in one or more ..... These amido carboxylic acids can be prepared by the Schotten-Baumann acylation reaction .... terephthalic acid dimethyl ester; terephthalic acidbisglycol ester and the like.
azelainsav (azelasav) - Azelainsäure - Azelaic acid
Azelaic acid is an organic compound with the formula (CH2)7(CO2H)2. This saturated dicarboxylic acid exists as a white powder. It is found in wheat, rye, and barley. It is a precursor to diverse industrial products including polymers, plasticizers, as well as being a component of a number of hair and skin conditioners
Azelaic acid is used to treat mild to moderate acne, both comedonal acne and inflammatory acne. It belongs to a class of medication called dicarboxylic acids. It works by killing acne bacteria that infect skin pores. It also decreases the production of keratin, which is a natural substance that promotes the growth of acne bacteria.Azelaic acid is also used as a topical gel treatment for rosacea, due to its ability to reduce inflammation.It clears the bumps and swelling caused by Rosacea.
Brand names for azelaic acid include Azepur99 (Azelaic Products), Azetec99 (Azeco Technologies USA), Azaclear (azelaic acid and niacinamide, Epikintics), AzClear Action (Ego Pharmaceuticals), Azelex (Allergan), White Action cream (SynCare), Finacea (Intendis/Berlex Laboratories), Finevin (Intendis/Berlex Laboratories), Melazepam (Strata Dermatologics), Skinoren (Intendis), Ezanic (Intas), and Azaderm (MUP) .
Chemical formula: C9H16O4
CAS Number: 123-99-9
http://www.webmd.com/skin-problems-and-treatments/acne/acne-...
Moderate to severe acne
Sometimes acne needs treatment with stronger medicines or a combination of therapies. Deeper blemishes, such as nodules and cysts, are more likely to leave scars. As a result, your doctor may give you oral antibiotics sooner to start the healing process. This kind of acne may need a combination of several therapies. Treatment for moderate to severe acne may include:
Applying benzoyl peroxide.
Draining of large pimples and cysts by a doctor.
Applying prescription antibiotic gels, creams, or lotions.
Applying prescription retinoids.
Applying azelaic acid.
Taking prescription oral antibiotics.
Taking prescription oral retinoids (such as isotretinoin).
--------------------------------------------------
Note added at 44 mins (2016-02-14 15:07:58 GMT)
--------------------------------------------------
lipidization of simple and di-functional amino acids
www.ukm.my/mjas/v17_n1/Wahid.pdf
The diamidoester of azelaic acid with L-alanine ethyl ester, L-valine ethyl ...
Patent WO2001051011A2 - Condensation products of ...
www.google.com/patents/WO2001051011A2?cl=en -
Condensation products of proteins, whereby azelaic acid is used .... Typically, the reaction in which it is a Schotten-Baumann acylation is carried out at ..... as citric acid, malic acid, tartaric acid or tartaric acid diethyl ester, and zinc glycinate.
[PDF]Synthesis of N-Azeloyl Amino Acids Ethyl Esters and their ...
file.upi.edu/Direktori/FPMIPA/.../PO16_Zainab_IDRIS.pdf
Acylation of glycine ethyl ester hydrochloride with azelaic acid dichloride ... ester and L-glutamic acid diethyl ester were in good yield when prepared ... conventional Schotten-Baumann reaction condition i.e. by reacting 1 mol of azelaic acid.
--------------------------------------------------
Note added at 46 mins (2016-02-14 15:10:25 GMT)
--------------------------------------------------
I have to make a phone call, our collegue Mr. György Bánhegyi is a professor in Chemistry. Let me ask something as the "ester" is disturbing.
--------------------------------------------------
Note added at 47 mins (2016-02-14 15:10:58 GMT)
--------------------------------------------------
Azelaic acid - I am CF 5 but I am not sure about the following two.
Catalytic Approaches to the Synthesis of Amide Bonds - Opus
opus.bath.ac.uk/29484/1/UnivBath_PhD_2012_C.L.Allen.pdf
by C Allen -
Results and Discussion IV - Amides from Carboxylic Acids. 112. 5.1 Introduction. 113 .... spray is synthesised using the Schotten-Baumann reaction.
Patent US5051466 - Internal mold release compositions ...
www.google.com/patents/US5051466
Sep 24, 1991 - It is released from the salt by the reaction of the amine with the ... The present invention provides for an improvement in one or more ..... These amido carboxylic acids can be prepared by the Schotten-Baumann acylation reaction .... terephthalic acid dimethyl ester; terephthalic acidbisglycol ester and the like.
azelainsav (azelasav) - Azelainsäure - Azelaic acid
Azelaic acid is an organic compound with the formula (CH2)7(CO2H)2. This saturated dicarboxylic acid exists as a white powder. It is found in wheat, rye, and barley. It is a precursor to diverse industrial products including polymers, plasticizers, as well as being a component of a number of hair and skin conditioners
Azelaic acid is used to treat mild to moderate acne, both comedonal acne and inflammatory acne. It belongs to a class of medication called dicarboxylic acids. It works by killing acne bacteria that infect skin pores. It also decreases the production of keratin, which is a natural substance that promotes the growth of acne bacteria.Azelaic acid is also used as a topical gel treatment for rosacea, due to its ability to reduce inflammation.It clears the bumps and swelling caused by Rosacea.
Brand names for azelaic acid include Azepur99 (Azelaic Products), Azetec99 (Azeco Technologies USA), Azaclear (azelaic acid and niacinamide, Epikintics), AzClear Action (Ego Pharmaceuticals), Azelex (Allergan), White Action cream (SynCare), Finacea (Intendis/Berlex Laboratories), Finevin (Intendis/Berlex Laboratories), Melazepam (Strata Dermatologics), Skinoren (Intendis), Ezanic (Intas), and Azaderm (MUP) .
Chemical formula: C9H16O4
CAS Number: 123-99-9
http://www.webmd.com/skin-problems-and-treatments/acne/acne-...
Moderate to severe acne
Sometimes acne needs treatment with stronger medicines or a combination of therapies. Deeper blemishes, such as nodules and cysts, are more likely to leave scars. As a result, your doctor may give you oral antibiotics sooner to start the healing process. This kind of acne may need a combination of several therapies. Treatment for moderate to severe acne may include:
Applying benzoyl peroxide.
Draining of large pimples and cysts by a doctor.
Applying prescription antibiotic gels, creams, or lotions.
Applying prescription retinoids.
Applying azelaic acid.
Taking prescription oral antibiotics.
Taking prescription oral retinoids (such as isotretinoin).
--------------------------------------------------
Note added at 44 mins (2016-02-14 15:07:58 GMT)
--------------------------------------------------
lipidization of simple and di-functional amino acids
www.ukm.my/mjas/v17_n1/Wahid.pdf
The diamidoester of azelaic acid with L-alanine ethyl ester, L-valine ethyl ...
Patent WO2001051011A2 - Condensation products of ...
www.google.com/patents/WO2001051011A2?cl=en -
Condensation products of proteins, whereby azelaic acid is used .... Typically, the reaction in which it is a Schotten-Baumann acylation is carried out at ..... as citric acid, malic acid, tartaric acid or tartaric acid diethyl ester, and zinc glycinate.
[PDF]Synthesis of N-Azeloyl Amino Acids Ethyl Esters and their ...
file.upi.edu/Direktori/FPMIPA/.../PO16_Zainab_IDRIS.pdf
Acylation of glycine ethyl ester hydrochloride with azelaic acid dichloride ... ester and L-glutamic acid diethyl ester were in good yield when prepared ... conventional Schotten-Baumann reaction condition i.e. by reacting 1 mol of azelaic acid.
--------------------------------------------------
Note added at 46 mins (2016-02-14 15:10:25 GMT)
--------------------------------------------------
I have to make a phone call, our collegue Mr. György Bánhegyi is a professor in Chemistry. Let me ask something as the "ester" is disturbing.
--------------------------------------------------
Note added at 47 mins (2016-02-14 15:10:58 GMT)
--------------------------------------------------
Azelaic acid - I am CF 5 but I am not sure about the following two.
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