Glossary entry

English term or phrase:

bone isomer

German translation:

(Bestimmung des) Knochen-Isoenzyms/Knochen-AP

Added to glossary by Christine Lam
Feb 7, 2009 23:43
15 yrs ago
1 viewer *
English term

bone isomer

English to German Medical Medical (general)
in a schedule for study procedures:

if alk phos is elevated, run bone isomer
Proposed translations (German)
3 +3 (Bestimmung des) Knochen-Isoenzyms
References
background info

Discussion

Marga Shaw Feb 8, 2009:
My concern is that the term "bone isomer" is non-sensical whilst I agree with Andrea that most likely ref. made here is to "alk. phosphatase bone isoenzyme". However, this should be pointed out to/queried with the author/client as "isomer" and "isoenzyme" are different by definition.
Christine Lam (asker) Feb 8, 2009:
...and yes, alk phos means alkaline phosphatase
Christine Lam (asker) Feb 8, 2009:
thank you both for your suggestions. This is a foot note relating to lab tests, specifically to the serum chemistry
Ingeborg Gowans (X) Feb 7, 2009:
alk phos, meaning alkaline phosphate by any chance? Isomer seems to refer to some standardization? But a bit more context might be helpful?

Proposed translations

+3
33 mins
Selected

(Bestimmung des) Knochen-Isoenzyms

... ist meine Vermutung ohne näheren Kontext.
Ist die AlkPhos im Blut erhöht kann das auf eine Erkrankung in verschiedenen organen hinweisen. Zur genaueren Abklärung werden Knochen- oder Leber-Isoenzyme getestet.

Die Bestimmung der Aktivität z. B. des Leber- bzw. des Knochenisoenzyms ist von besonderer diagnostischer Bedeutung bei der Untersuchung von Erkrankungen der Leber bzw. des Knochenenzyms. Die Erkrankungen bewirken einen Anstieg der AP-Aktivität im Plasma, da unter diesen Voraussetzungen von der Leber bzw. den Knochen in verstärktem Maße Alkalische Phosphatase an das Plasma abgegeben wird. Der Anstieg der AP-Aktivität des Leber- oder des Knochen-Isoenzyms im Plasma kann demnach dazu dienen, eine Erkrankung dieser Gewebe zu erkennen.
http://www.patent-de.com/19921203/DE4117619A1.html

Alkaline phosphatase is an enzyme found in all tissues. Tissues with particularly high concentrations of ALP include the liver, bile ducts, placenta, and bone.

Damaged or diseased tissue releases enzymes into the blood, so serum ALP measurements can be abnormal in many conditions, including bone disease and liver disease. Serum ALP is also increased in some normal circumstances (for example, during normal bone growth) or in response to a variety of drugs.

There are multiple varieties of ALP (Alkaline phosphatase) , called isoenzymes. Different types of isoenzymes, each with different structures, are found in different tissues (for example, liver and bone ALP isoenzymes have different structures) and can be quantified separately in the laboratory. To differentiate the location of damaged or diseased tissue in the body, ALP isoenzyme testing must be done.
http://arthritis-symptom.com/procedures/alk-phos.htm




Peer comment(s):

agree Marga Shaw : >So würde ich es auch sehen, jedoch mit einer Einschränkung (s.o. unter "Clarification Request")
9 hrs
Danke, Marga. Eine Abklärung mit dem Kunden ist sicherlich notwendig
agree Gabriele Beckmann : mit Marga
10 hrs
Dankeschön, Gabriele :))
agree MMUlr : Heißt "bone alkaline phosphatase" oder bAP oder BAP -> http://www.quidel.com/libraries/wp/BH/Usefulness_BAP_In_Mana... - deutsch Knochen-AP -> http://www.med4you.at/laborbefunde/lbef2/lbef_alkalische_pho...
2 days 11 hrs
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4 KudoZ points awarded for this answer. Comment: "Vielen Dank!"

Reference comments

31 mins
Reference:

background info

http://www.drkaslow.com/html/alkaline_phosphatase.html
maybe the context here sheds some light on the procedure
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