by selectively targeting

Spanish translation: actuando de manera selectiva/selectivamente sobre

GLOSSARY ENTRY (DERIVED FROM QUESTION BELOW)
English term or phrase: by selectively targeting
Spanish translation:actuando de manera selectiva/selectivamente sobre
Entered by: Jorge Arteaga M.D.

17:08 Nov 6, 2009
English to Spanish translations [PRO]
Medical - Medical: Pharmaceuticals / oncología
English term or phrase: by selectively targeting
Es un texto farmacéutico sobre un tratamiento complementario en el linfoma difuso de células B grandes.

¿Cómo traduciríais "by selectively targeting"?

The study drug is a novel oral derivative of rapamycin that acts as a signal transduction inhibitor by selectively targeting mTOR

Gracias
Annette F
Spain
Local time: 14:16
actuando de manera selectiva/selectivamente sobre
Explanation:
"targeting" aquí se refiere a actuar teniendo como blanco/objetivo una molécula
Selected response from:

Jorge Arteaga M.D.
United States
Local time: 08:16
Grading comment
Gracias!!
4 KudoZ points were awarded for this answer



Summary of answers provided
5 +6actuando de manera selectiva/selectivamente sobre
Jorge Arteaga M.D.
4al seleccionar como objetivo...
Yaotl Altan
4apuntando selectivamente a...
Ana Castro
4al dirigir especificamente
HannahBreckner
Summary of reference entries provided
liz askew

  

Answers


5 mins   confidence: Answerer confidence 4/5Answerer confidence 4/5
al seleccionar como objetivo...


Explanation:


Yaotl Altan
Mexico
Local time: 06:16
Specializes in field
Native speaker of: Native in SpanishSpanish, Native in ItalianItalian
PRO pts in category: 232
Login to enter a peer comment (or grade)

6 mins   confidence: Answerer confidence 4/5Answerer confidence 4/5
apuntando selectivamente a...


Explanation:
como que este medicamento es bastante específico y "ataca" selectivamente...

suerte!


    Reference: http://www.wordreference.com
Ana Castro
Spain
Local time: 14:16
Works in field
Native speaker of: Spanish
Login to enter a peer comment (or grade)

12 mins   confidence: Answerer confidence 5/5 peer agreement (net): +6
actuando de manera selectiva/selectivamente sobre


Explanation:
"targeting" aquí se refiere a actuar teniendo como blanco/objetivo una molécula

Jorge Arteaga M.D.
United States
Local time: 08:16
Specializes in field
Native speaker of: Native in SpanishSpanish
PRO pts in category: 255
Grading comment
Gracias!!

Peer comments on this answer (and responses from the answerer)
agree  Lizette Britz: 100% de acuerdo!
50 mins

agree  Andrea Vanya
2 hrs

agree  Cristian Garcia
2 hrs

agree  Daphne Consigliere, R.N.: very nice! :)
2 hrs

agree  Miguel Armentia
13 hrs

agree  Teresa Mozo
18 hrs
Login to enter a peer comment (or grade)

7 hrs   confidence: Answerer confidence 4/5Answerer confidence 4/5
al dirigir especificamente


Explanation:
"dirigir" me parece un buen equivalente

Example sentence(s):
  • Al dirigir los fármacos específicamente a las células cancerosas
HannahBreckner
United Kingdom
Local time: 13:16
Specializes in field
Native speaker of: English
Login to enter a peer comment (or grade)




Reference comments


4 mins peer agreement (net): +1
Reference

Reference information:
http://209.85.229.132/search?q=cache:_GaoLWo9zwwJ:www.siicsa...

--------------------------------------------------
Note added at 25 mins (2009-11-06 17:34:46 GMT)
--------------------------------------------------

En concordancia ya se demostró en varios estudios preclínicos la eficiencia antitumoral del uso combinado de los agentes biomoduladores y la quimioterapia metronómica. Los nuevos resultados de los ensayos clínicos que se encuentran en progresión estimularán el desarrollo de estas estrategias dirigidas al estroma.


Moreover, daily low dose administration of cytotoxic drugs, referred to as metronomic chemotherapy, turned out to exhibit antiangiogenetic effects as well and may thereby complement the novel strategies using biomodulators for stroma targeting. Accordingly, in several preclinical studies, the antitumoral efficiency of combinatorial use of both biomodulating drugs and metronomic chemotherapy has already been demonstrated. New results of ongoing clinical trials will encourage the developing of such stroma-targeted therapies.



--------------------------------------------------
Note added at 27 mins (2009-11-06 17:36:20 GMT)
--------------------------------------------------

#
TRATAMIENTO ONCOLOGICO NO RADICAL DIRIGIDO AL ESTROMA
- [ Translate this page ]
Además de los efectos antitumorales directos, el mTOR dirigido también parece inhibir la neoangiogénesis en el cáncer. El mTOR desempeña un papel clave en ...
www.siicsalud.com/dato/dat053/07730005.htm - Cached - Similar
#
Revista Venezolana de Oncología - Terapia Biológica en Cáncer ...
- [ Translate this page ]
Los tratamientos dirigidos selectivamente a esta familia de receptores pueden ... EVEROLIMUS (INHIBIDOR DE MTOR) CON LETROZOL. La quinasa mTor interviene en ...
www.scielo.org.ve/scielo.php?pid=S0798...script=sci... - Cached - Similar
by O MÉDICO-HEMATÓLOGO - Related articles - All 2 versions

liz askew
United Kingdom
Works in field
Native speaker of: Native in EnglishEnglish
PRO pts in category: 257

Peer comments on this reference comment (and responses from the reference poster)
agree  jokie
14 mins
Login to enter a peer comment (or grade)



Login or register (free and only takes a few minutes) to participate in this question.

You will also have access to many other tools and opportunities designed for those who have language-related jobs (or are passionate about them). Participation is free and the site has a strict confidentiality policy.

KudoZ™ translation help

The KudoZ network provides a framework for translators and others to assist each other with translations or explanations of terms and short phrases.


See also:
Term search
  • All of ProZ.com
  • Term search
  • Jobs
  • Forums
  • Multiple search